Recombinant Human SYK (N-GST tag)
Cat. No.
Z500377
Unit
10 µg
Price
$370.00
Specifications
| Description | SYK is a non-receptor protein tyrosine kinase that is widely expressed in hematopoietic cells. It is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. In B cells, SYK plays a crucial role in intracellular signal transduction induced by oxidative stress as well as antigen receptor engagement . SYK has been shown to act as a potential tumor suppressor in breast cancer. Absence of SYK protein in primary breast tumors is correlated with poor outcomes. SYK deficient cells have increased motility that is restored to normalcy by replacement with wild-type SYK . |
| SKU | Z500377 |
| Accession Number | NM_003177 |
| Appearance | Liquid |
| Formulation | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
| Gene Symbol | SYK |
| Source | Insect cells |
| Molecular Weight | 100.0 kDa |
| Species | Human (H. sapiens) |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
| Storage | Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Unit Quantity | 10 µg |
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