siRNA Technology
siRNAs are powerful tools for gene silencing and can be delivered to the target cell or host via a variety of methods including ready-to-use lentivirus, AAV, adenovirus, or direct transfection of DNA plasmids or double stranded RNA (dsRNA). Our unique convergent dual promoter system avoids the need to design hair-pin loop shRNA structures, streamlining cloning and knockdown of the target gene.
We offer a comprehensive collection of human, mouse, and rat siRNAs pre-designed for knockdown of your gene of interest. Can't find what you're looking for? We can generate Custom siRNA vectors and viruses tailored to your experiment.
Search our extensive collection of siRNA Technology products using Gene symbol or Accession number:
Products
Lentivirus siRNA Expression Tools
AAV siRNA Expression Tools
Resources
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Viral Expression Systems BrochureIntroductory Guide -
piLenti-siRNA-GFP vector map
Vector Map -
Lenti-siRNA Expression Systems Manual
Click to Download
Publications
| 01 | Hindbrain insulin controls feeding behaviour Eerola K. et al. Molecular Metabolism (2022). DOI: 10.1016/j.molmet.2022.101614. Pubmed: 36244663 |
| 02 | FSH blockade improves cognition in mice with Alzheimer's disease. Xiong J., et al. Nature (2022). DOI: 10.1038/s41586-0225-04463-0. Pubmed: PMC9940301. |
| 03 |
HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution. |