CHIR99021
Cat. No.
G611
Unit
2.0 mg
Price
$63.00
Specifications
Cat. No. G611
Name CHIR99021
Price $63.00
Unit 2.0 mg
Category Reagents and Chemicals
Description
Formula Name
6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile
 
Formula                          
C22H18Cl2N8
 
Molecular Weight         
465 g/mol
 
Stability                       
2 years
 
QC                                           
MR and Mass Spectrometry
 
Function                                  
Glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo.
 
Small Molecule Action         
Reprogramming
Concentration 10mM in DMSO (~430ul)
Purity 99%
Storage Condition

-20°C

Caution For Research Use Only, not for therapeutic or diagnostic purposes.
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References
  • Shen, J., Lyu, C., Zhu, Y., Feng, Z., Zhang, S., Hoyle, D. L., … Wang, Z. Z. "Defining early hematopoietic‐fated primitive streak specification of human pluripotent stem cells by the orchestrated balance of Wnt, activin, and BMP signaling" Journal of Cellular Physiology 234(9):16136–16147 (2019). DOI: 10.1002/jcp.28272.