Recombinant Human GGF2
Cat. No.
Z101655
Unit
Price
$660.00
Specifications
| Description | Neuregulins (NDF, heregulin, GGF ARIA, or SMDF) are EGF-like growth and differentiation factors that signal through tyrosine kinase receptors of the ErbB family. The ErbB2 and ErbB4 receptors cooperate in transmission of neuregulin-1 signals in the heart, whereas ErbB2 and ErbB3 cooperate in neural crest cells. |
| SKU | Z101655 |
| Unit quantity | 50 µg |
| Family | Other Growth Factors/Cytokines |
| Aliases |
GGF2, Pro-neuregulin-1, membrane-bound isoform, Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, HRG, Neu differentiation factor, Sensory and motor neuron-derived factor Recombinant Human Glial Growth Factor (GGF2) |
| Gene Symbol | GGF2 |
| Gene ID | 3084 |
| Accession Number | Q02297 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 34 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method. |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Recombinant GGF2 was lyophilized from a 0.2 μm filtered 0.02M PB, pH 7.0. |
| Function | The ED(50) was determined by the dose-dependent phosphorylation of human MCF-7 cells was found to be < 20 ng/mL, corresponding to a specific activity of 5.0 x 10^4 Units/mg. |
| Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
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