Recombinant Human MIP-3 alpha (CCL20)
Cat. No.
Z100705
Unit
Price
$246.00
Specifications
| Description | Macrophage inflammatory protein (MIP)-3/CCL20, also known as liver and activation-regulated chemokine (LARC) or Exodus, is a member of the CC chemokine subfamily initially noted to be expressed in human liver, lung, appendix, and tonsillar crypts. MIP-3 is selectively chemotactic for CD34(+) bone marrow cell-derived immature DCs and CD45RO(+) memory T cells that express the cognate receptor CCR6. MIP-3 produced at sites of inflammation may chemoattract CCR6-expressing immature DCs to the subepithelial region of mucosal surfaces. |
| SKU | Z100705 |
| Unit quantity | 25 µg |
| Family | Chemokine-beta Family (CC) |
| Aliases |
Beta-chemokine exodus-1, MIP3 alpha, CC chemokine LARC, Liver and activation-regulated chemokine, MIP-3-alpha, Small-inducible cytokine A20, SCYA20 Recombinant Human Macrophage Inflammatory Protein-3 Alpha (CCL20) |
| Gene Symbol | CCL20 |
| Gene ID | 6364 |
| Accession Number | P78556 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 8 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method. |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Recombinant CCL20 was lyophilized from a 0.2 μm filtered 20 mM PB,100 mM NaCl solution pH 7.5. |
| Function | Determined by its ability to chemoattract human monocytes using a concentration range of 2-40 ng/mL. |
| Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
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