Recombinant Human NRG4 (E. coli)
Cat. No.
Z100905
Unit
Price
$660.00
Specifications
| Description |
Neuregulins (NDF, heregulin, GGF ARIA, or SMDF) are EGF-like growth and differentiation factors that signal through tyrosine kinase receptors of the ErbB family. The ErbB2 and ErbB4 receptors cooperate in transmission of neuregulin-1 signals in the heart, whereas ErbB2 and ErbB3 cooperate in neural crest cells. |
| SKU | Z100905 |
| Unit quantity | 50 µg |
| Family | Other Growth Factors/Cytokines |
| Aliases |
Pro-neuregulin-4, membrane-bound isoform, Pro-NRG4, NRG4 |
| Gene Symbol | NRG4 |
| Gene ID | 145957 |
| Accession Number | Q8WWG1 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 7 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
| Purity |
>95% as determined by SDS-PAGE |
| Formulation | Lyophilized from a 0.2 μm filtered PBS, pH 7.4 solution. |
| Function | The ED(50) was determined by the dose-dependent proliferation of Raji cells and was found to be <0.05ng/mL. |
| Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
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