Recombinant Rat Eotaxin (CCL11) (E. coli)
Cat. No.
Z300145
Unit
Price
$89.00
Specifications
Description Eotaxin belongs to the platelet factor-4 family of chemokines. The gene symbol is SCYA11. This factor is referred to also as Eotaxin-1 and has been renamed CCL11. Eotaxin induces substantial accumulation of eosinophils in the skin without significantly affecting the accumulation of neutrophils. Eotaxin is a potent stimulator of both guinea pig and human eosinophils in vitro. The Eotaxin receptor is a G-protein-coupled receptor selectively expressed in human eosinophils.
SKU Z300145
Unit quantity 20 µg
Family Chemokine-beta Family (CC)
Aliases C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11, Scya11
Gene Symbol CCL11
Gene ID 29397
Accession Number P97545
Source E. coli
Species Rat (R. norvegicus)
Appearance Lyophilized Powder
Molecular Weight 8 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 μm filtered solution in PBS
Function Activity was determined by the ability to chemoattract human peripheral blood eosinophils using a concentration range of 0.1-20 ng/mL.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
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